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Palliative care utilization, transfusion burden, and <scp>end‐of‐life</scp> care for patients with multiple myeloma

Authors :
Geoffrey McInturf
Kimberly Younger
Courtney Sanchez
Charles Walde
Al‐Ola Abdallah
Nausheen Ahmed
Leyla Shune
Douglas W. Sborov
Amandeep Godara
Brian McClune
Christian T. Sinclair
Ghulam Rehman Mohyuddin
Source :
European Journal of Haematology. 109:559-565
Publication Year :
2022
Publisher :
Wiley, 2022.

Abstract

Despite treatment advances, multiple myeloma (MM) remains a significant source of morbidity and mortality. We aimed to examine specialist palliative care (SPC) involvement and end-of-life care for patients with MM.We assessed all deceased patients with a diagnosis of MM who received care at a single institution from January 2010 to December 2019 and assessed SPC involvement.We reviewed 456 deceased patients. Overall, 207 patients (45.4%) received SPC visits by clinicians during their disease, and 153 (33.5%) were on MM treatment in the month before death. Median time from SPC consultation to death was 1 month, with 42 (9.2%) of patients receiving SPC visits 6 or more months before death. Amongst the patients for which a place of death was reported (351), 117 (33.3%) died in the acute care setting. Outpatient SPC did not correlate with a reduction of death in the acute care setting. In the group of patients who received outpatient SPC, 22/84 (26.2%) died in an acute care setting, whereas 95/267 (35.5%) patients who did not receive outpatient SPC also died in an acute care setting, (p = .11).In our analysis of the entire trajectory of the MM patient experience from diagnosis to death, we found low rates of SPC involvement and a significant proportion of patients receiving aggressive care at end-of-life. While there is no clear correlation that SPC involvement impacted the rate of acute care deaths or decreased utilization of MM treatment in the last month of life, further prospective research on optimal utilization of SPC is required.

Details

ISSN :
16000609 and 09024441
Volume :
109
Database :
OpenAIRE
Journal :
European Journal of Haematology
Accession number :
edsair.doi.dedup.....fbff4ebfe3a49a5c2be3d837c20d7c1c