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A novel prognostic nomogram utilizing the 2018 FIGO staging system for cervical cancer: A large multicenter study
- Source :
- International Journal of Gynecology & Obstetrics. 155:86-94
- Publication Year :
- 2021
- Publisher :
- Wiley, 2021.
-
Abstract
- OBJECTIVE To evaluate the prognostic performance of the revised 2018 FIGO staging system for cervical cancer. METHODS This retrospective multicenter study enrolled cervical cancer patients with 2009 FIGO Stage IA1-IIA2 who underwent surgeries between January 2006 and December 2017 in four tertiary hospitals. Patients were restaged according to the 2018 FIGO staging system by reviewing their medical data. RESULTS Of 3238 cervical cancer patients included, 1841 (56.9%) patients were restaged: 641 (34.9%) due to tumor size, 544 (29.5%) due to lymph node metastasis, 614 (33.4%) due to the inconsistency between pre- and postoperative assessments, and 42 due to the cancellation of invasion width in Stage IA. After restaging, a clear tendency of decreased recurrence-free survival (RFS) and overall survival (OS) with increasing stage was observed. Multivariate Cox analysis showed that 2018 FIGO stage, parametrial involvement, and histology were independent prognostic factors for both OS and RFS (P
- Subjects :
- medicine.medical_specialty
Uterine Cervical Neoplasms
Lymph node metastasis
03 medical and health sciences
0302 clinical medicine
Figo staging
medicine
Humans
030212 general & internal medicine
Stage (cooking)
Neoplasm Staging
Retrospective Studies
Cervical cancer
030219 obstetrics & reproductive medicine
Tumor size
business.industry
Parametrial
Obstetrics and Gynecology
General Medicine
Nomogram
Prognosis
medicine.disease
Nomograms
Multicenter study
Female
Radiology
business
Subjects
Details
- ISSN :
- 18793479 and 00207292
- Volume :
- 155
- Database :
- OpenAIRE
- Journal :
- International Journal of Gynecology & Obstetrics
- Accession number :
- edsair.doi.dedup.....fc598a50cff38228efa31fcc6a140b21