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No more hypoglycaemia on days with physical activity and unrestricted diet when using a closed‐loop system for 12 weeks: A post hoc secondary analysis of the multicentre, randomized controlled Diabeloop WP7 trial
- Source :
- Diabetes, Obesity & Metabolism, Diabetes, Obesity and Metabolism, Diabetes, Obesity and Metabolism, 2021, 23 (9), pp.2170-2176. ⟨10.1111/dom.14442⟩, Diabetes, Obesity and Metabolism, Wiley, 2021, 23 (9), pp.2170-2176. ⟨10.1111/dom.14442⟩
- Publication Year :
- 2021
- Publisher :
- Blackwell Publishing Ltd, 2021.
-
Abstract
- International audience; Objective: To investigate the efficacy of the Diabeloop Generation-1 (DBLG1) closed-loop system to control the hypoglycaemia induced by physical activity (PA) in real-life conditions.Methods: This was a post-hoc analysis of the Diabeloop WP7 multicentre randomized controlled trial. Glycaemic outcomes were compared between days with and without PA in 56 patients with type 1 diabetes (T1D) using DBLG1 for 12 weeks. After the patient announces a PA, DBLG1 reduces insulin delivery and, if necessary, calculates the amount of preventive carbohydrates (CHO).Results: Daily time spent in the interstitial glucose range
- Subjects :
- Blood Glucose
[SDV.MHEP.PHY] Life Sciences [q-bio]/Human health and pathology/Tissues and Organs [q-bio.TO]
type 1 diabetes
[SDV]Life Sciences [q-bio]
Endocrinology, Diabetes and Metabolism
medicine.medical_treatment
physical activity
030204 cardiovascular system & hematology
insulin pump therapy
law.invention
0302 clinical medicine
Endocrinology
Randomized controlled trial
law
Secondary analysis
Medicine
Insulin
[SDV.MHEP.EM] Life Sciences [q-bio]/Human health and pathology/Endocrinology and metabolism
Cross-Over Studies
Brief Report
artificial pancreas
[SDV.MHEP.EM]Life Sciences [q-bio]/Human health and pathology/Endocrinology and metabolism
closed‐loop system
3. Good health
glycaemic control
Anesthesia
continuous glucose monitoring
Closed-loop system
Post hoc
Physical activity
030209 endocrinology & metabolism
Artificial pancreas
03 medical and health sciences
Insulin Infusion Systems
Internal Medicine
[SDV.MHEP.PHY]Life Sciences [q-bio]/Human health and pathology/Tissues and Organs [q-bio.TO]
Humans
Hypoglycemic Agents
Exercise
physical intervention
Type 1 diabetes
business.industry
medicine.disease
Hypoglycemia
Diet
Diabetes Mellitus, Type 1
[SDV.SPEE] Life Sciences [q-bio]/Santé publique et épidémiologie
randomized controlled trial
[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie
Brief Reports
business
Closed loop
[SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
hypoglycaemia
Subjects
Details
- Language :
- English
- ISSN :
- 14631326 and 14628902
- Volume :
- 23
- Issue :
- 9
- Database :
- OpenAIRE
- Journal :
- Diabetes, Obesity & Metabolism
- Accession number :
- edsair.doi.dedup.....fc5f795cae6404cd1f3ae26bebee76cb