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Semiconducting CuO Nanotubes: Synthesis, Characterization, and Bifunctional Photocathodic Enzymatic Bioanalysis

Authors :
Wei-Wei Zhao
Yuan-Cheng Zhu
Jing-Juan Xu
Ling Zhang
Yanyu Liang
Hong-Yuan Chen
Source :
Analytical Chemistry. 90:5439-5444
Publication Year :
2018
Publisher :
American Chemical Society (ACS), 2018.

Abstract

This work reports the synthesis, characterization, and application of bifunctional semiconducting CuO nanotubes (NTs) electrode for innovative synergized cathodic photoelectrochemical (PEC) enzymatic bioanalysis. Specifically, CuO NTs electrode was fabricated by surface oxidation of the copper foil in an alkaline aqueous solution with (NH4)2S2O8 and then annealed in air at 200 °C. After the subsequent coupling with the model enzyme of xanthine oxidase (XOD), the resulted photocathodic enzyme biosensor exhibited good analytical performance of rapid response, high stability, and good sensitivity. Especially, due to the unique catalytic property of CuO toward H2O2, a novel enzymatic cascade design between biological catalyst (XOD as natural enzyme) and biomimetic catalyst (CuO as the peroxidase mimetics) was constructed, and the dual-catalyst system with special synergy effect could achieve the cathodic PEC guanine bioanalysis with enhanced efficiency. In the determination, the cathodic photocurrent was foun...

Details

ISSN :
15206882 and 00032700
Volume :
90
Database :
OpenAIRE
Journal :
Analytical Chemistry
Accession number :
edsair.doi.dedup.....fc6333810f25736c8ae6df2757b3b0af
Full Text :
https://doi.org/10.1021/acs.analchem.8b00742