Back to Search
Start Over
Molecular Epidemiology of Tuberculosis in Kaohsiung City Located at Southern Taiwan, 2000-2008
- Source :
- PLoS ONE, PLoS ONE, Vol 10, Iss 1, p e0117061 (2015)
- Publication Year :
- 2015
- Publisher :
- Public Library of Science, 2015.
-
Abstract
- BACKGROUND We present the first comprehensive analysis of Mycobacterium tuberculosis (MTB) isolates circulating in southern Taiwan. In this 9-year population-based study, the TB situation in the Kaohsiung region was characterized by genotypic analysis of 421 MTB isolates. METHODS All 421 isolates of MTB were analyzed by spoligotyping and MIRU-VNTR typing. Drug-resistance patterns were also analyzed. RESULTS The percentage of EAI (East African-Indian) strains increased across sampling years (2000-2008) in southern Taiwan, whereas the proportion of Beijing lineages remained unchanged. Clustering was more frequent with EAI genotype infections (odds ratio = 3.6, p
- Subjects :
- Tuberculosis
Population
Taiwan
lcsh:Medicine
Drug resistance
Polymorphism, Single Nucleotide
Microbiology
Mycobacterium tuberculosis
Antibiotic resistance
Genotype
Drug Resistance, Bacterial
medicine
Humans
education
lcsh:Science
Retrospective Studies
education.field_of_study
Molecular Epidemiology
Multidisciplinary
Molecular epidemiology
biology
business.industry
lcsh:R
medicine.disease
biology.organism_classification
Anti-Bacterial Agents
Bacterial Typing Techniques
Multiple drug resistance
Streptomycin
lcsh:Q
business
Genome, Bacterial
Research Article
Subjects
Details
- Language :
- English
- ISSN :
- 19326203
- Volume :
- 10
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- PLoS ONE
- Accession number :
- edsair.doi.dedup.....fc6efdc9fa2da818a5c7d707ccd99cda