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Sitafloxacin Activity against Helicobacter pylori Isolates, Including Those with gyrA Mutations
- Source :
- Antimicrobial Agents and Chemotherapy. 53:3097-3099
- Publication Year :
- 2009
- Publisher :
- American Society for Microbiology, 2009.
-
Abstract
- Sitafloxacin showed MICs of less than or equal to 0.5 μg/ml against 105 isolates of Helicobacter pylori , including 44 isolates with mutations in the gyrA gene. The highest MICs for garenoxacin and levofloxacin were 8 and 64 times, respectively, higher than the highest MICs observed for sitafloxacin.
- Subjects :
- Sitafloxacin
Ofloxacin
Levofloxacin
Microbial Sensitivity Tests
Drug resistance
DNA gyrase
Garenoxacin
Microbiology
chemistry.chemical_compound
medicine
Pharmacology (medical)
Antibacterial agent
Pharmacology
Helicobacter pylori
biology
bacterial infections and mycoses
biology.organism_classification
Virology
Anti-Bacterial Agents
Infectious Diseases
chemistry
DNA Gyrase
Susceptibility
Mutation
Fluoroquinolones
medicine.drug
Subjects
Details
- ISSN :
- 10986596 and 00664804
- Volume :
- 53
- Database :
- OpenAIRE
- Journal :
- Antimicrobial Agents and Chemotherapy
- Accession number :
- edsair.doi.dedup.....fc91a0e1cffc10c405a917ab07522883
- Full Text :
- https://doi.org/10.1128/aac.01552-08