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Foamy gland pancreatic ductal adenocarcinoma diagnosed on EUS-FNA: A histochemical, immunohistochemical, and molecular report
Foamy gland pancreatic ductal adenocarcinoma diagnosed on EUS-FNA: A histochemical, immunohistochemical, and molecular report
- Publication Year :
- 2012
-
Abstract
- The foamy gland pattern (FGP) may impart to pancreatic ductal adenocarcinoma (PDA) a deceptively benign appearance. Thus, its diagnosis on FNA is challenging. A case of PDA with FGP, that was suspected on Diff Quik smears, diagnosed on cell-block preparation and confirmed by ancillary stains and molecular techniques, is here reported. The diagnostic interpretation of foamy atypical cells on direct smears may benefit from cell block preparation and from ancillary techniques.
- Subjects :
- Cytoplasm
Pathology
medicine.medical_specialty
Histology
Pancreatic ductal adenocarcinoma
Pancreas Ductal Adenocarcinoma
Adenocarcinoma
Pathology and Forensic Medicine
Proto-Oncogene Proteins p21(ras)
Proto-Oncogene Proteins
pancreatic adenocarcinoma
medicine
Carcinoma
Humans
foamy gland pattern
Endoscopic Ultrasound-Guided Fine Needle Aspiration
False Negative Reactions
Cell block
Cell Nucleus
business.industry
Atypical cells
pancreatic adenocarcinoma,EUS-FNA,foamy gland pattern,special stains,molecular cytopathology
Diff-Quik
Sequence Analysis, DNA
General Medicine
Middle Aged
pancreas ductal adenocarcinoma
medicine.disease
EUS-FNA
Pancreatic Neoplasms
molecular cytopathology
Mutation
ras Proteins
Immunohistochemistry
Female
business
Carcinoma, Pancreatic Ductal
Subjects
Details
- Database :
- OpenAIRE
- Accession number :
- edsair.doi.dedup.....fcded07018482ef62c93dfd2ecabf022