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Cardiopulmonary Exercise Testing as a Tool for Diagnosing Pulmonary Hypertension in Patients with Dilated Cardiomyopathy
- Source :
- Annals of Noninvasive Electrocardiology : The Official Journal of the International Society for Holter and Noninvasive Electrocardiology, Inc
- Publication Year :
- 2015
-
Abstract
- Background Recently, it has become increasingly recognized that pulmonary hypertension (PH) is a particularly threatening result of left-sided heart disease. However, there have been few investigations of the impact of cardiopulmonary exercise testing (CPX) variables on PH in dilated cardiomyopathy (DCM). We evaluated the usefulness of crucial CPX variables for detecting elevated pulmonary arterial pressure (PAP) in patients with DCM. Methods Ninety subjects with DCM underwent cardiac catheterization and CPX at our hospital. Receiver operator characteristic (ROC) analysis was performed to assess the ability of CPX variables to distinguish between the presence and absence of PH. Results Overall mean values were: mean PAP (mPAP), 18.0 ± 9.6 mmHg; plasma brain natriuretic peptide, 233 ± 295 pg/mL; and left ventricular ejection fraction, 30.2 ± 11.0%. Patients were allocated to one of two groups on the basis of mean PAP, namely DCM without PH [mean PAP (mPAP)
- Subjects :
- Cardiomyopathy, Dilated
Male
medicine.medical_specialty
Cardiac Catheterization
Heart disease
medicine.medical_treatment
Hypertension, Pulmonary
030204 cardiovascular system & hematology
Sensitivity and Specificity
03 medical and health sciences
Ventricular Dysfunction, Left
0302 clinical medicine
Oxygen Consumption
Physiology (medical)
Internal medicine
pulmonary hypertension
cardiopulmonary exercise testing
Medicine
Humans
030212 general & internal medicine
Cardiac catheterization
Ejection fraction
peak VO2
Receiver operating characteristic
business.industry
Dilated cardiomyopathy
Stroke Volume
General Medicine
Odds ratio
Original Articles
Middle Aged
medicine.disease
Brain natriuretic peptide
Pulmonary hypertension
dilated cardiomyopathy
Cardiology
Exercise Test
Female
Original Article
Cardiology and Cardiovascular Medicine
business
Biomarkers
Subjects
Details
- ISSN :
- 1542474X
- Volume :
- 21
- Issue :
- 3
- Database :
- OpenAIRE
- Journal :
- Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc
- Accession number :
- edsair.doi.dedup.....fd0c37902519f19d03a105ee05b0a7ca