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Curcuma longa rhizome extract and Curcumin reduce the adhesion of Acanthamoeba triangularis trophozoites and cysts in polystyrene plastic surface and contact lens
- Source :
- International Journal for Parasitology: Drugs and Drug Resistance, Vol 14, Iss, Pp 218-229 (2020), International Journal for Parasitology: Drugs and Drug Resistance
- Publication Year :
- 2020
- Publisher :
- Elsevier, 2020.
-
Abstract
- Curcuma longa and Curcumin have been documented to have a wide spectrum of pharmacological effects, including anti-Acanthamoeba activity. Hence, this study sought to explore the anti-adhesion activity of C. longa extract and Curcumin against Acanthamoeba triangularis trophozoites and cysts in plastic and contact lenses. Our results showed that C. longa extract and Curcumin significantly inhibited the adhesion of A. triangularis trophozoites and cysts to the plastic surface, as investigated by the crystal violet assay (P<br />Graphical abstract Image 1
- Subjects :
- 0301 basic medicine
Curcumin
Contact Lenses
030231 tropical medicine
Acanthopodia
Acanthamoeba
Curcuma longa extract
Article
lcsh:Infectious and parasitic diseases
03 medical and health sciences
chemistry.chemical_compound
0302 clinical medicine
Curcuma
Acanthamoeba triangularis
Animals
Pharmacology (medical)
lcsh:RC109-216
Crystal violet
Trophozoites
Pharmacology
biology
Chemistry
Plant Extracts
Adhesion
Contact lens
biology.organism_classification
Molecular biology
Rhizome
030104 developmental biology
Infectious Diseases
Polystyrenes
Parasitology
Polystyrene
Plastics
Subjects
Details
- Language :
- English
- ISSN :
- 22113207
- Volume :
- 14
- Database :
- OpenAIRE
- Journal :
- International Journal for Parasitology: Drugs and Drug Resistance
- Accession number :
- edsair.doi.dedup.....fd716f4d734e648d642047ed6468529b