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Curcuma longa rhizome extract and Curcumin reduce the adhesion of Acanthamoeba triangularis trophozoites and cysts in polystyrene plastic surface and contact lens

Authors :
T. Jimoh
Christophe Wiart
Veeranoot Nissapatorn
Suthinee Sangkanu
Chonticha Romyasamit
Watcharapong Mitsuwan
Polrat Wilairatana
Abolghasem Siyadatpanah
Sunil Kayesth
Muhammad Nawaz
Maria de Lourdes Pereira
Mark S. Butler
Mohammed Rahmatullah
Chalermpon Kaewjai
Source :
International Journal for Parasitology: Drugs and Drug Resistance, Vol 14, Iss, Pp 218-229 (2020), International Journal for Parasitology: Drugs and Drug Resistance
Publication Year :
2020
Publisher :
Elsevier, 2020.

Abstract

Curcuma longa and Curcumin have been documented to have a wide spectrum of pharmacological effects, including anti-Acanthamoeba activity. Hence, this study sought to explore the anti-adhesion activity of C. longa extract and Curcumin against Acanthamoeba triangularis trophozoites and cysts in plastic and contact lenses. Our results showed that C. longa extract and Curcumin significantly inhibited the adhesion of A. triangularis trophozoites and cysts to the plastic surface, as investigated by the crystal violet assay (P<br />Graphical abstract Image 1

Details

Language :
English
ISSN :
22113207
Volume :
14
Database :
OpenAIRE
Journal :
International Journal for Parasitology: Drugs and Drug Resistance
Accession number :
edsair.doi.dedup.....fd716f4d734e648d642047ed6468529b