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Effect of Tributyltin, Cadmium, and Their Combination on Physiological Responses in Juvenile Grass Carp
- Source :
- Journal of aquatic animal health. 28(3)
- Publication Year :
- 2016
-
Abstract
- Tributyltin (TBT) and cadmium (Cd) are two common pollutants in aquatic environments. This study was designed to examine the physiological responses of juvenile Grass Carp Ctenopharyngodon idella to TBT, Cd, and their combination. Fish were apportioned into a control group, a TBT group (7.5 μg/L), a Cd group (2.97 mg/L), and a TBT-Cd group (7.5 μg/L TBT, 2.97 mg/L Cd(2+)) for 7 d. The following activities were measured: Na(+),K(+)-ATPase in gill tissues; nitric oxide synthase (NOS), acetylcholinesterase (AChE), and monoamine oxidase (MAO) in brain tissues; and lipid peroxidation (LPO), malondialdehyde (MDA), total antioxidative capacity (T-AOC), and glutathione (GSH) in liver tissues. Cadmium-induced stress was suggested by alterations in antioxidant responses (MDA, LPO, and T-AOC) and neurological parameters (AChE, MAO, and NOS). Cadmium also induced Na(+),K(+)-ATPase and GSH activity. Compared with the responses among the Cd group, the combination of TBT and Cd not only decreased the level of GSH and Na(+),K(+)-ATPase but also increased the levels of MDA, LPO, AChE, MAO, and NOS. These results suggest that a combination of TBT and Cd could reduce the adverse effects of Cd on Grass Carp. However, the exact mechanisms for the combined effects TBT and Cd on these biomarkers require further investigation. Received September 28, 2015; accepted April 17, 2016.
- Subjects :
- 0301 basic medicine
Gills
medicine.medical_specialty
Antioxidant
Carps
medicine.medical_treatment
chemistry.chemical_element
010501 environmental sciences
Aquatic Science
01 natural sciences
Antioxidants
Toxicology
Lipid peroxidation
03 medical and health sciences
chemistry.chemical_compound
Internal medicine
medicine
Animals
0105 earth and related environmental sciences
Cadmium
biology
Brain
Glutathione
Malondialdehyde
biology.organism_classification
Grass carp
Nitric oxide synthase
030104 developmental biology
Endocrinology
chemistry
Liver
biology.protein
Tributyltin
Trialkyltin Compounds
Biomarkers
Water Pollutants, Chemical
Subjects
Details
- ISSN :
- 15488667
- Volume :
- 28
- Issue :
- 3
- Database :
- OpenAIRE
- Journal :
- Journal of aquatic animal health
- Accession number :
- edsair.doi.dedup.....fde7d66af0d9e7554c00b8379b8b8c98