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Does tetanus vaccination contribute to reduced severity of the COVID-19 infection?
- Source :
- Medical Hypotheses
- Publication Year :
- 2020
-
Abstract
- We present the hypothesis to the scientific community actively designing clinical trials and recommending public health guidelines to control the pandemic that – “Tetanus vaccination may be contributing to reduced severity of the COVID-19 infection” – and urge further research to validate or invalidate the effectiveness of the tetanus toxoid vaccine against COVID-19. This hypothesis was revealed by an explainable artificial intelligence system unleashed on open public biomedical datasets. As a foundation for scientific rigor, we describe the data and the artificial intelligence system, document the provenance and methodology used to derive the hypothesis and also gather potentially relevant data/evidence from recent studies. We conclude that while correlations may not be reason for causation, correlations from multiple sources is more than a serendipitous co-incidence that is worthy of further and deeper investigation.
- Subjects :
- 0301 basic medicine
medicine.medical_specialty
Artificial Intelligence System
COVID-19 Vaccines
Databases, Pharmaceutical
Models, Biological
Severity of Illness Index
Rigour
Article
03 medical and health sciences
0302 clinical medicine
Tetanus Toxin
Artificial Intelligence
Clostridium tetani
Pandemic
medicine
Tetanus Toxoid
Humans
Causation
Pandemics
Sequence Homology, Amino Acid
Tetanus
SARS-CoV-2
Public health
Vaccination
Drug Repositioning
COVID-19
General Medicine
medicine.disease
Clinical trial
030104 developmental biology
Spike Glycoprotein, Coronavirus
Psychology
030217 neurology & neurosurgery
Clinical psychology
Subjects
Details
- ISSN :
- 15322777
- Volume :
- 146
- Database :
- OpenAIRE
- Journal :
- Medical hypotheses
- Accession number :
- edsair.doi.dedup.....fec2782d976b2d3067db22b8b287acf0