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Does tetanus vaccination contribute to reduced severity of the COVID-19 infection?

Authors :
Sreenivas R. Sukumar
Kristyn J. Maschhoff
Christopher D. Rickett
Source :
Medical Hypotheses
Publication Year :
2020

Abstract

We present the hypothesis to the scientific community actively designing clinical trials and recommending public health guidelines to control the pandemic that – “Tetanus vaccination may be contributing to reduced severity of the COVID-19 infection” – and urge further research to validate or invalidate the effectiveness of the tetanus toxoid vaccine against COVID-19. This hypothesis was revealed by an explainable artificial intelligence system unleashed on open public biomedical datasets. As a foundation for scientific rigor, we describe the data and the artificial intelligence system, document the provenance and methodology used to derive the hypothesis and also gather potentially relevant data/evidence from recent studies. We conclude that while correlations may not be reason for causation, correlations from multiple sources is more than a serendipitous co-incidence that is worthy of further and deeper investigation.

Details

ISSN :
15322777
Volume :
146
Database :
OpenAIRE
Journal :
Medical hypotheses
Accession number :
edsair.doi.dedup.....fec2782d976b2d3067db22b8b287acf0