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Continuous thrombocytopenia after SARS-CoV-2 nucleic acid negative in a non-severe COVID-19 patient for several months
- Source :
- BMC Infectious Diseases, BMC Infectious Diseases, Vol 20, Iss 1, Pp 1-5 (2020)
- Publication Year :
- 2020
- Publisher :
- BioMed Central, 2020.
-
Abstract
- Background Thrombocytopenia was common in the coronavirus disease (Covid-19) patients during the infection, especially in severe COVID-19 patients, but was less in the non-severe Covid-19 patients. However, the platelet count would be restored after antivirus treatment. In this paper, we report continuous thrombocytopenia in a non-severe Covid-19 case after a negative nucleic acid test for Covid-19. Case presentation A non-severe COVID-19 patient had the platelet continuous decrease for several months after the SARS-CoV-2 nucleic acid turning negative, and without well response to the glucocorticoid. The dynamic change of platelet count followed that of the lymphocyte count. After excluding the medicines possibility, immune system disorders, other specific virus infection and specific antibody of platelet, the thrombocytopenia continuously lasted for several months. The upward trend did not begin until June 2020 and she took the tapering dose of prednisone under the instruction of the hematologist. Conclusion Excluding other potentialities inducing thrombocytopenia, we highly hypothesized the SARS-CoV-2 may cause thrombocytopenia by disturbing the immune system to induce the thrombocytopenia in our report,, which needs longer time to restore the immune system and platelet count via the glucocorticoid. We firstly reported this case in order to contribute the clinician to better deal with the patients like this.
- Subjects :
- Lymphocyte
Pneumonia, Viral
Case Report
030204 cardiovascular system & hematology
medicine.disease_cause
Virus
lcsh:Infectious and parasitic diseases
Betacoronavirus
03 medical and health sciences
0302 clinical medicine
Immune system
Prednisone
medicine
Humans
lcsh:RC109-216
Platelet
Lymphocyte Count
030212 general & internal medicine
Pandemics
Coronavirus
Continuous thrombocytopenia
medicine.diagnostic_test
Platelet Count
business.industry
Non-severe COVID-19
SARS-CoV-2
COVID-19
Nucleic acid test
Middle Aged
Thrombocytopenia
Infectious Diseases
medicine.anatomical_structure
Immunology
RNA, Viral
Female
Coronavirus Infections
business
Glucocorticoid
medicine.drug
Subjects
Details
- Language :
- English
- ISSN :
- 14712334
- Volume :
- 20
- Database :
- OpenAIRE
- Journal :
- BMC Infectious Diseases
- Accession number :
- edsair.doi.dedup.....fee7a025f0a93416582ce4b93a371ce5