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Nature of subretinal fluid in patients undergoing vitrectomy for macular hole: a cytopathological and optical coherence tomography study
- Source :
- Clinicalexperimental ophthalmology. 36(9)
- Publication Year :
- 2009
-
Abstract
- Background: Outer retinal defects (ORDs) may occur after surgical closure of full thickness macular holes (FTMH) and be associated with delayed visual recovery. This may be due to the nature of the subretinal fluid (SRF) cuff and/or the loss of retinal elements. Methods: Vitrectomy with internal limiting membrane (ILM) peel was performed for FTMH. After fluid-air exchange, SRF was either aspirated from the hole (group 1) or left in situ (group 2). The SRF specimens obtained were examined by light microscopy and correlated with optical coherence tomography (OCT). Results: In group 1, cellular material was found in 6 out of 12 cases. Photoreceptors were seen in 3 and macrophages in 3 cases. Nine of 12 holes closed and ORDs were seen in 3 of these. In group 2, 7 out of 8 holes closed, with 4 having ORD. There was no difference in visual acuity (LogMAR) for closed holes at 3 months between groups 1 (0.61, range 0.3–1) and 2 (0.51, range 0.3–0.78) nor between patients with ORD (0.57, range 0.3–1.0) or without ORD (0.57, range 0.3–1.0). Conclusions: SRF from FTMH may contain macrophages and photoreceptors. Such photoreceptor loss may contribute to reduced retinal function. ORDs occur commonly in spite of fluid aspiration, but their presence is still compatible with good vision. Aspiration of SRF did not appear to confer added benefit in this series.
- Subjects :
- Male
medicine.medical_specialty
Visual acuity
genetic structures
medicine.medical_treatment
Visual Acuity
Vitrectomy
Retina
chemistry.chemical_compound
Postoperative Complications
Optical coherence tomography
Retinal Diseases
Ophthalmology
medicine
Full-thickness macular hole
Humans
Macular hole
Aged
medicine.diagnostic_test
business.industry
Macrophages
Retinal detachment
Retinal
Anatomy
Middle Aged
medicine.disease
Retinal Perforations
eye diseases
Treatment Outcome
chemistry
Female
sense organs
medicine.symptom
business
Retinal Defect
Tomography, Optical Coherence
Photoreceptor Cells, Vertebrate
Subjects
Details
- ISSN :
- 14429071
- Volume :
- 36
- Issue :
- 9
- Database :
- OpenAIRE
- Journal :
- Clinicalexperimental ophthalmology
- Accession number :
- edsair.doi.dedup.....ff541980b8b48847e6a2506f3f701665