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Prognostic outcome of routine clinical noninvasive Multidetector row Computed Tomography Coronary Angiography in Patients with suspected coronary artery disease: a 2-years follow-up study
- Source :
- Europe PubMed Central
- Publication Year :
- 2011
- Publisher :
- Springer-Verlag, 2011.
-
Abstract
- The aim of the study was to assess the prognostic value of multidetector-row CT coronary angiography (MDCT-CA) in patients with suspected coronary artery disease (CAD) in a routine clinical context.A total of 125 patients (82 men, age 57.4±10.3 years) with suspected CAD underwent MDCT-CA. All patients were assessed for cardiovascular risk factors, symptoms and coronary calcium score. A 2-year follow-up study for the occurrence of major adverse cardiac events was performed.According to the Morise pretest score, 76 patients (60.8%) were at intermediate risk. Patients with suspected CAD presented the following prognostic outcome (p0.0001): in 41 patients with normal coronary arteries at MDCT-CA, the event rate was 0%; five of 49 patients with nonobstructive CAD had major cardiac events; two of 35 patients with obstructive CAD suffered cardiac death and 19 underwent revascularisation. At multivariate analysis, the presence of obstructive CAD is the only significant independent prognostic variable (hazard ratio, 10.1393; 95% confidence interval 3.2189-31.9379; p0.0001).Routine clinical MDCT-CA provides an excellent prognostic value at 2-year follow-up in patients with normal coronary arteries. The cardiac event rate increases with CAD severity.
- Subjects :
- Coronary angiography
Male
Malattia aterosclerotica coronarica
medicine.medical_specialty
Context (language use)
Coronary Artery Disease
Coronary Angiography
Sensitivity and Specificity
Coronary artery disease
Predictive Value of Tests
Internal medicine
medicine
Image Processing, Computer-Assisted
Humans
Radiology, Nuclear Medicine and imaging
In patient
Valore prognostico
cardiovascular diseases
Coronary artery disease, Prognostic value, Coronary angiography, Multidetector row computed tomography
Neuroradiology
medicine.diagnostic_test
business.industry
Follow up studies
Interventional radiology
General Medicine
Multidetector row computed tomography
Middle Aged
medicine.disease
Prognosis
Predictive value of tests
Angiografia coronarica
cardiovascular system
Cardiology
Female
Radiology
Tomografia computerizzata multistrato
business
Tomography, X-Ray Computed
Settore MED/36 - Diagnostica Per Immagini E Radioterapia
Prognostic value
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Journal :
- Europe PubMed Central
- Accession number :
- edsair.doi.dedup.....ff85602e2979bcd8c40f80883f6f1787