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Arterial Stiffness is Related to Impaired Exercise Capacity in Patients With Coronary Artery Disease and History of Myocardial Infarction
- Source :
- Heart, Lung and Circulation. 28:1614-1621
- Publication Year :
- 2019
- Publisher :
- Elsevier BV, 2019.
-
Abstract
- Background Augmented arterial stiffness and reduced cardiorespiratory fitness are associated with increased morbidity and mortality from coronary artery disease (CAD). The relationship between exercise capacity and arterial stiffness is independent of known influencing variables in CAD. This study aimed to analyse the interaction between exercise capacity, arterial stiffness and early vascular ageing in patients with CAD. Methods This cross-sectional study included 96 CAD patients with myocardial infarction (55.9 ± 10.9 years, 81 men) referred to cardiac rehabilitation. Arterial stiffness was assessed using carotid-femoral pulse wave velocity (cf-PWV). Cardiopulmonary exercise test was performed to measure VO2peak. Comparisons of VO2peak across cf-PWV risk threshold values (high-risk cf-PWV ≥ 10 m/s) and tertile groups, and across cf-PWV threshold values and age groups (younger group Results Patients with high-risk cf-PWV had lower VO2peak than those with low-risk cf-PWV (p Conclusions Arterial stiffening is associated with lower cardiorespiratory fitness in CAD patients with myocardial infarction. When its values are above risk threshold, exercise capacity is impaired regardless of the relationship between age and arterial stiffness.
- Subjects :
- Male
Pulmonary and Respiratory Medicine
medicine.medical_specialty
medicine.medical_treatment
Myocardial Infarction
Coronary Artery Disease
Pulse Wave Analysis
030204 cardiovascular system & hematology
Coronary artery disease
Electrocardiography
03 medical and health sciences
Vascular Stiffness
0302 clinical medicine
Risk Factors
Internal medicine
medicine
Humans
In patient
cardiovascular diseases
030212 general & internal medicine
Myocardial infarction
Pulse wave velocity
Retrospective Studies
Exercise Tolerance
Rehabilitation
Portugal
business.industry
Cardiorespiratory fitness
Middle Aged
Exercise capacity
medicine.disease
Survival Rate
Carotid Arteries
Cross-Sectional Studies
Exercise Test
cardiovascular system
Arterial stiffness
Cardiology
Female
Morbidity
Cardiology and Cardiovascular Medicine
business
Follow-Up Studies
Subjects
Details
- ISSN :
- 14439506
- Volume :
- 28
- Database :
- OpenAIRE
- Journal :
- Heart, Lung and Circulation
- Accession number :
- edsair.doi.dedup.....ff93662197fae7f01e0b9fc5fa3bd1c0