Back to Search Start Over

Stress echocardiographic results predict risk of reinfarction early after uncomplicated acute myocardial infarction: Large-scale multicenter study

Authors :
Giacomo Chiarandà
Mauro Raciti
Maria Grazia Sclavo
Luis Felipe de Moura Duarte
Francesco Chiarella
Nicola Gandolfo
Seveso G
Federico Bianchi
Alessandro Pingitore
Silva Severi
Rosa Sicari
Cristina Vassalle
Salvatore Pirelli
Giovanni Minardi
Maria José Bento de Sousa
Leonardo Bolognese
Ornella Magaia
Eugenio Picano
Patrizia Landi
Franca Margaria
Mario Previtali
Source :
Journal of the American College of Cardiology. 26:908-913
Publication Year :
1995
Publisher :
Elsevier BV, 1995.

Abstract

Objectives. This study sought to assess the value of dipyridamole echocardiography in predicting reinfarction in patients evaluated early after uncomplicated acute myocardial infarction. Background. The identification of future nonfatal reinfarction seems an elusive target for physiologic testing. However, a large sample population is needed to detect minor differences in phenomena with a low event rate. Methods. We assessed the value of dipyridamole echocardiography in predicting reinfarction in 1,080 patients (mean [±SD] age 56 ± 9 years; 926 men, 154 women) evaluated early (10 ± 5 days) after uncomplicated acute myocardial infarction and followed up for 14 ± 10 months. Results. Submaximal studies due to limiting side effects occurred in 14 patients (1.3%); these test results were included in the analysis. Results of dipyridamole echocardiography were positive in 475 patients (44%). During follow-up, there were 50 reinfarctions: 45 nonfatal, 5 fatal (followed by cardiac death ≤4 days after reinfarction). Reinfarction (either nonfatal or fatal) occurred in 30 patients with positive and 20 with negative results (6.3% vs. 3.3%, p Conclusions. Dipyridamole echocardiographic positivity identifies patients evaluated early after uncomplicated acute myocardial infarction at higher risk of reinfarction, especially fatal reinfarction.

Details

ISSN :
07351097
Volume :
26
Database :
OpenAIRE
Journal :
Journal of the American College of Cardiology
Accession number :
edsair.doi.dedup.....ffe050f0471a79f232969ca9b50d3431