GSTM1 polymorphism is related to risks of nasopharyngeal cancer and laryngeal cancer: a meta-analysis

Fengying Zhang,1,* Xijiang Wu,2,* Jinming Niu,1 Xiufeng Kang,3 Liya Cheng,1 Yanchun Lv,1 Meimei Wu1 1Otorhinolaryngological Department, Wei Fang Traditional Chinese Hospital, Weifang, Shandong Province, China; 2Otorhinolaryngological Department, Shouguang Peoples Hospital, Shouguang, Shandong Province, China; 3Medical insurance office, Shouguang Peoples Hospital, Shouguang, Shandong Province, China *These authors contributed equally to this work Background: Accumulating data have reported that GSTM1 polymorphism may be related to nasopharyngeal cancer (NPC) and laryngeal cancer (LC). This meta-analysis was performed to investigate the relationship between GSTM1 polymorphism and risks of NPC and LC. Methods: Pubmed, Embase, and China National Knowledge Infrastructure (CNKI) databases were searched for potential articles. Odds ratios (ORs) and 95% confidence intervals (CIs) were used to evaluate the relationship of GSTM1 polymorphism with the risks of NPC and LC. I2>50% or P