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RUTHENIUM (II) COMPLEXES WITH HIGH ANTITUMORAL AND ANTIMETASTATIC ACTIVITIES

Authors :
SIGEA SRL
MESTRONI GIOVANNI
ALESSIO ENZO
SAVA GIANNI
IENGO ELISABETTA
ZORZET SONIA
BERGAMO ALBERTA

Abstract

The present invention is related to Ruthenium derived antitumoral compounds with high antimetastatic activity and with low toxicity for the host. It is described the use of inorganic Ruthenium complexes in the therapy of solid tumors, in particular of those tumors characterized by high metastatizing ability. Pharmaceutical compositions containing Ruthenium complexes in formulations suitable for the administration and a kit for the preparation of such complexes at the moment of use or immediately before use, are moreover described.

Subjects

Subjects :
C07F15/00

Details

Database :
OpenAIRE
Accession number :
edsair.epopatstat....9a56df65b5a0357c23d1f1a558f0d796