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Genomic Characterization of Aeromonas veronii Provides Insights into Taxonomic Assignment and Reveals Widespread Virulence and Resistance Genes throughout the World

Authors :
Gouveia, José Cleves da Silva Maia
Gabriel Amorim de Albuquerque Silva
Letícia Stheffany de Barros Cunha
Gisele Veneroni Gouveia
Aristóteles Góes-Neto
Bertram Brenig
Fabrício Almeida Araújo
Flávia Aburjaile
Rommel Thiago Jucá Ramos
Siomar Castro Soares
Vasco Ariston de Carvalho Azevedo
Mateus Matiuzzi da Costa
João José de Simoni
Source :
Antibiotics; Volume 12; Issue 6; Pages: 1039
Publication Year :
2023
Publisher :
Multidisciplinary Digital Publishing Institute, 2023.

Abstract

Aeromonas veronii is a Gram-negative bacterial species that causes disease in fish and is nowadays increasingly recurrent in enteric infections of humans. This study was performed to characterize newly sequenced isolates by comparing them with complete genomes deposited at the NCBI (National Center for Biotechnology Information). Nine isolates from fish, environments, and humans from the São Francisco Valley (Petrolina, Pernambuco, Brazil) were sequenced and compared with complete genomes available in public databases to gain insight into taxonomic assignment and to better understand virulence and resistance profiles of this species within the One Health context. One local genome and four NCBI genomes were misidentified as A. veronii. A total of 239 virulence genes were identified in the local genomes, with most encoding adhesion, motility, and secretion systems. In total, 60 genes involved with resistance to 22 classes of antibiotics were identified in the genomes, including mcr-7 and cphA. The results suggest that the use of methods such as ANI is essential to avoid misclassification of the genomes. The virulence content of A. veronii from local isolates is similar to those complete genomes deposited at the NCBI. Genes encoding colistin resistance are widespread in the species, requiring greater attention for surveillance systems.

Details

Language :
English
ISSN :
20796382
Database :
OpenAIRE
Journal :
Antibiotics; Volume 12; Issue 6; Pages: 1039
Accession number :
edsair.multidiscipl..0d6942e50798032d53042bc6a8e30a63
Full Text :
https://doi.org/10.3390/antibiotics12061039