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Enantioselective Dehydrochlorination of delta-Hexachlorocyclohexane and delta-Pentachlorocyclohexene by LinA1 and LinA2 from Sphingobium indicum B90A
- Publisher :
- American Society for Microbiology
-
Abstract
- delta-Hexachlorocyclohexane (delta-HCH), one of the prevalent isomers of technical HCH, was enantioselectively dehydrochlorinated by the dehydrochlorinases LinA1 and LinA2 from Sphingobium indicum B90A to the very same delta-pentachlorocyclohexene enantiomer. Racemic delta-pentachlorocyclohexene, however, was transformed with opposite enantioselectivities by the two enzymes. A transformation pathway based on an anti-1,2-elimination, followed by a syn-1,4-elimination and a subsequent syn-1,2-elimination is postulated.
- Subjects :
- lindane
Biodegradation
pesticides
Subjects
Details
- Database :
- OpenAIRE
- Accession number :
- edsair.od.......185..dacaf067940922293b5c2b63a3a5646a