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High Asymptomatic Carriage With the Omicron Variant in South Africa

Authors :
Garrett, Nigel
Tapley, Asa
Andriesen, Jessica
Seocharan, Ishen
Fisher, Leigh H
Bunts, Lisa
Espy, Nicole
Wallis, Carole L
Randhawa, April Kaur
Miner, Maurine D
Ketter, Nzeera
Yacovone, Margaret
Goga, Ameena
Huang, Yunda
Hural, John
Kotze, Philip
Bekker, Linda Gail
Gray, Glenda E
Corey, Lawrence
Ubuntu Study Team
Source :
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, vol 75, iss 1
Publication Year :
2022
Publisher :
eScholarship, University of California, 2022.

Abstract

We report a 23% asymptomatic severe acute respiratory syndrome coronavirus 2 (SARS CoV-2) Omicron carriage rate in participants being enrolled into a clinical trial in South Africa, 15-fold higher than in trials before Omicron. We also found lower CD4 + T-cell counts in persons with human immunodeficiency virus (HIV) strongly correlated with increased odds of being SARS-CoV-2 polymerase chain reaction (PCR) positive.

Details

Database :
OpenAIRE
Journal :
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, vol 75, iss 1
Accession number :
edsair.od.......325..2227aa9921b91fb8d733710644357dea