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Urine Tenofovir Levels Measured by a Novel Immunoassay Predict HIV Protection

Authors :
Stalter, Randy M
Baeten, Jared M
Donnell, Deborah
Spinelli, Matthew A
Glidden, David V
Rodrigues, Warren C
Wang, Guohong
Vincent, Michael
Mugo, Nelly
Mujugira, Andrew
Marzinke, Mark
Hendrix, Craig
Gandhi, Monica
Partners PrEP Study Team
Source :
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, vol 72, iss 3
Publication Year :
2020
Publisher :
eScholarship, University of California, 2020.

Abstract

New tools are needed to support PrEP adherence for individuals at risk for HIV, including those that enable provision of real-time feedback. In a large, completed PrEP trial, adequate urine tenofovir levels measured by a novel immunoassay predicted HIV protection and showed good sensitivity and specificity for detectable plasma tenofovir.

Details

Database :
OpenAIRE
Journal :
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, vol 72, iss 3
Accession number :
edsair.od.......325..50d25b6cca5e2ca51c8eaff783333827