Insulin pump in treating patients with diabetes type 1

Tip 1 šećerna bolest (T1ŠB) nastaje zbog samorazaranja beta stanica gušterače. Uzrok nastanka T1ŠB-a je međudjelovanje nasljednih čimbenika i čimbenika okoliša. Primjenom inzulinske pumpe u oboljelih od T1ŠB-a poboljšava se kakvoća života i postiže se bolja regulacija glikemije, što smanjuje rizik razvoja komplikacija.U ovom radu istražena je promjena vrijednosti glikoliziranog hemoglobina (HbA1c) prije i nakon primjene inzulinske pumpe, njen utjecaj na promjenu indeksa tjelesne uhranjenosti (BMI-SDS), učestalost pojave teških hipoglikemija i ketoacidoza (DKA). Vrijednosti HbA1c-a su se statistički značajno smanjile nakon primjene inzulinske pumpe. BMI-SDS je očekivano značajno porastao nakon primjene inzulinske pumpe s obzirom na slobodu unosa namirnica. Učestalost pojave teških hipoglikemijskih kriza i DKA u naših ispitanika vrlo je mala, s obzirom na rezultate istraživanja drugih centara u svijetu.
Diabetes type 1 (T1D) originates from beta cell destruction. Heredity and environmental factors influence the genesis of T1D. The use of an insulin pump in patients with T1D improves their quality of life and attains better regulation of glycaemia, which reduces the risk of complications. In this study we documented the variation in HbA1c values before and after using insulin pumps and its influence on body mass index (BMI-SDS) changes, the frequency of severe hypoglycaemia and ketoacidosis (DKA). HbA1c values were greatly reduced after insulin pump use. BMI-SDS confirmed the expected significant growth using the insulin pump in regards to free eating habits. The frequency of severe hypoglycaemia and DKA in our patients was very small compared to results published in other diabetic centres throughout the world.