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Successful Fecal Microbiota Transplantation in a Patient with Severe Complicated Infection after Liver Transplantation

Authors :
Schneider, Kai Markus
Wirtz, Theresa H
Kroy, Daniela
Albers, Stefanie
Neumann, Ulf Peter
Strowig, Till
Sellge, Gernot
Trautwein, Christian
Helmholtz-Zentrum für Infektionsforschung GmbH, Inhoffenstr. 7, 38124 Braunschweig, Germany.
Source :
Case reports in gastroenterology
Publication Year :
2018

Abstract

infection (CDI) represents one of the most common healthcare-associated infections. Due to increasing numbers of recurrences and therapy failures, CDI has become a major disease burden. Studies have shown that fecal microbiota transplantation (FMT) can both be a safe and highly efficacious therapy for patients with therapy-refractory CDI. However, patients undergoing solid organ transplantation are at high risk for CDI due to long-term immunosuppression, previous antibiotic therapy, and proton pump inhibitor use. Additionally, these patients may be especially prone to adverse events related to FMT. Here, we report a successful FMT in a patient with severe therapy-refractory CDI after liver transplantation.

Details

Language :
English
Database :
OpenAIRE
Journal :
Case reports in gastroenterology
Accession number :
edsair.od......1146..3ff245568749da9972659141b1d024cd