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A single dose of ketorolac during surgery may suppress cancer relapse : something for nothing?

Authors :
Forget, Patrice
UCL - (SLuc) Service d'anesthésiologie
UCL - SSS/IREC - Institut de recherche expérimentale et clinique
UCL - Faculté de médecine et médecine dentaire
De Kock, Marc
Machiels, Jean-Pascal
Berlière, Martine
Lauwerys, Bernard
Latinne, Dominique
Retsky, Michael
Sosnowski, Maurice
Publication Year :
2013

Abstract

Growth of tumors can accelerate during the peri-operative period. Understanding the complex role of inflammation and its consequences, positive and deleterious could lead to identify inflammatory-related biomarkers and therapeutic opportunities. In the works described here, we show how the neutrophil:lymphocyte ratio can be used as a prognostic factor before breast, lung and kidney cancer surgery, and how and why the intraoperative use of a single dose of ketorolac, a non-steroidal anti-inflammatory drug, has been identified as a promising way to prevent, at least some, postoperative cancer relapses. (MED - Sciences médicales) -- UCL, 2013

Details

Language :
English
Database :
OpenAIRE
Accession number :
edsair.od......1493..b19b3a07758932f4c5c82dceda53462e