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A Large Lumbar Adnexal Neoplasm Presenting Characteristics of Eccrine Poroma and Poroid Hidradenoma

Authors :
Michalinos, Adamantios Schizas, Dimitrios Sarakinos, Antonios and Athanasiadis, Georgios Spartalis, Eleftherios and Vlachodimitropoulos, Dimitrios Troupis, Theodore
Publication Year :
2017

Abstract

Poroma is a rare benign neoplasm that derives from eccrine sweat glands epithelium. Its histological subtypes, with respect to its position within skin layers, are eccrine poroma, hidroacanthoma simplex, poroid hidradenoma, and dermal duct tumor. Poromas commonly exhibit benign clinical behavior as they are usually small and asymptomatic and do not exhibit malignant behavior. Although their histological subtypes share similar histological characteristics, they rarely coexist in the same tumor. In this report we present the case of an unusual poroma in terms of histological and clinical behavior as it was large and presented histological characteristic of both eccrine poroma and poroid hidradenoma. Coexistence of different histologic subtypes in the same tumor indicates simultaneous tumorigenesis, differentiation from one cell type to another, or parallel differentiation from a common progenitor cell. Implications in treatment remain unknown partly due to the rarity of such cases.

Details

Language :
English
Database :
OpenAIRE
Accession number :
edsair.od......2127..02b6f8dbbf267ed95bb4425c4ce53e57