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Renal outcomes in patients with AL amyloidosis: Prognostic factors, renal response and the impact of therapy
- Publication Year :
- 2017
-
Abstract
- A staging system for patients with renal AL amyloidosis, based on eGFR (100) at 3 months had a 2-year progression to dialysis of 0% vs 24% for patients who either did not reduce to or still had a ratio >100 (P =.001); similar results were obtained by applying the same criteria at 6 months; thus, the evaluation of treatment effect on renal function may be identified early. Furthermore, primary bortezomib-based therapy was more effective than lenalidomide-based therapy, in terms of renal outcomes, especially in patients at intermediate renal risk, but without affecting overall survival. © 2017 Wiley Periodicals, Inc.
- Subjects :
- urologic and male genital diseases
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Accession number :
- edsair.od......2127..5b78df510290308b6041beb443a33a62