Liposominių nano-nešiklių su dihidrokvercetinu modeliavimas, charakterizavimas ir galimybių pritaikyti apsaugai nuo UV spinduliuotės poveikio tyrimas

[...]. The aim of the study. To design nano structured liposomal systems for dihydroquercetin delivery into the skin and evaluate their protective effects from UV rays damage using biological methods. The objectives of the study: 1. To evaluate the properties of dihydroquercetin for protecting cell cultures from UV irradiation in vitro. 2. To investigate and select plant based materials for skin penetration enhancement of dihydroquercetin. 3. To design lipid nano-carriers systems with dihydroquercetin containing selected skin penetration enhancers, perform optimisation and evaluate their quality. 4. To perform biopharmaceutical characterization of experimental formulations and evaluate their skin penetration into human skin ex vivo. 5. To evaluate the properties of experimental formulations for protecting cell cultures from UV irradiation in vitro. [...].