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The regulation of vascular endothelial growth factor by hypoxia and prostaglandin F₂α during human endometrial repair
- Source :
- Maybin, J A, Hirani, N, Brown, P, Jabbour, H N & Critchley, H O D 2011, ' The regulation of vascular endothelial growth factor by hypoxia and prostaglandin F₂α during human endometrial repair ', Journal of Clinical Endocrinology & Metabolism, vol. 96, no. 8, pp. 2475-83 . https://doi.org/10.1210/jc.2010-2971
- Publication Year :
- 2011
-
Abstract
- The human endometrium has an exceptional capacity for repeated repair after menses, but its regulation remains undefined. Premenstrually, progesterone levels fall and prostaglandin (PG) F₂α synthesis increases, causing spiral arteriole constriction. We hypothesized that progesterone withdrawal, PGF₂α, and hypoxia increase vascular endothelial growth factor (VEGF), an endometrial repair factor.
Details
- Language :
- English
- Database :
- OpenAIRE
- Journal :
- Maybin, J A, Hirani, N, Brown, P, Jabbour, H N & Critchley, H O D 2011, ' The regulation of vascular endothelial growth factor by hypoxia and prostaglandin F₂α during human endometrial repair ', Journal of Clinical Endocrinology & Metabolism, vol. 96, no. 8, pp. 2475-83 . https://doi.org/10.1210/jc.2010-2971
- Accession number :
- edsair.od......3094..2d0072435aade55cd227a17f2b93c431