Synthesis and characterization of New Dithiophosphonate Ligands

Perthiophosphonic acid anhydrides (PTPA) are used as a starting agent in the synthesis of phosphorus-sulfur compounds[1].These derivatives can be classified into dithiophosphates, dithiophosphinates and dithiophosphonates (DTPOA). In this survey, we synthesized new DTPOAs starting from PTPAs formerly synthesized by us ADDIN EN.CITE Bulat202232[32]323217Bulat, ElifSağlam, Ertuğrul GaziZeyrek, Celal TuğrulAkkoç, SenemZorlu, YunusDal, HakanNi(II) complexes with 1,3,2,4-dithiadiphosphetane 2,4-disulfide-based ligands: Structural insights, theoretical studies, and anticancer activitiesApplied Organometallic ChemistryApplied Organometallic Chemistrye6821361020220268-2605https://onlinelibrary.wiley.com/doi/abs/10.1002/aoc.6821https://doi.org/10.1002/aoc.6821[2,3]. In other words, new dithiophosphonic acids (HS2P((2,4-CH3O)2-C6H3)(ORn), HLx,y; RX1=n-propyl-, RX2=2-butyl-,Ry=methyl- were synthesized by reacting of 2,4-bis(3,4-dimethoxyphenyl)-1,3-dithia-2,4-diphosphetane 2,4-disulfide, (SAV-A1) and 2,4-bis(2,4-dimethoxyphenyl)-1,3-dithia-2,4-diphosphetane 2,4-disulfide, (SAV-A2) with aliphatic alcohols. All DTPOAs were transformed to relating to ammonium salts, [NH4Lx,y] (Scheme 1).