The charter of older people rights to participate in clinical trials

The results of initial literature review indicate thai elderly persons are underrepresented in the clinical trials on which clinical recommendations are based. This gave stimulus to perform the 'lncreasing the PaRticipation of the EIDerly In Clinical Trials' (PREDICD project, financed by the EU within the FP7. The goal of the PREDICT was to study reasons why older people are excluded from clinical trials based on age-related criteria and development of the charter including recommendations to prevent their exclusion. The project gathered investigators from 11 inslitutions in 9 countries: Czech Republic, lsrael, ltaly, Lithuania, the Netherlands, Poland, Romania, Spain, and the UK. Within the scope of PREDICT, first, to assess the scope of the problem the systematic review of literature was performed, !hen the opinion shared by the health care professionals, ethicists, and representatives of pharmaceutical industry on the possible reasons of underrepresentation of ald people in trials was examined, !hen finally the opinion of elderly patients and their caregivers were assessed. The analysis of gathered data enabled creation of PREDICT charter which contains recommendations aiming to increase the participation of elderly people in clinical trials.