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Clinical and Metabolic Characterization of Adults With Type 2 Diabetes by Age in the Glycemia Reduction Approaches in Diabetes: A Comparative Effectiveness Study (GRADE) Cohort

Authors :
Aroda, Vanita R.
Krause-Steinrauf, Heidi
Kazemi, Erin J.
Buse, John B.
Gulanski, Barbara I.
Florez, Hermes J.
Ahmann, Andrew J.
Loveland, Amy
Kuhn, Alexander
Lonier, Jacqueline Y.
Wexler, Deborah J.
Crandall, J.P.
McKee, M.D.
Behringer-Massera, S.
Brown-Friday, J.
Xhori, E.
Ballentine-Cargill, K.
Duran, S.
Estrella, H.
Gonzalez de la torre, S.
Lukin, J.
Phillips, L.S.
Burgess, E.
Olson, D.
Rhee, M.
Wilson, P.
Raines, T.S.
Boers, J.
Costello, J.
Maher-Albertelli, M.
Mungara, R.
Savoye, L.
White, C.A.
Gullett, C.
Holloway, L.
Morehead, F.
Person, S.
Sibymon, M.
Tanukonda, S.
Adams, C.
Ross, A.
Balasubramanyam, A.
Gaba, R.
Gonzalez Hattery, E.
Ideozu, A.
Jimenez, J.
Montes, G.
Wright, C.
Hollander, P.
Roe, E.
Jackson, A.
Smiley, A.
Burt, P.
Estrada, L.
Chionh, K.
Ismail-Beigi, F.
Falck-Ytter, C.
Sayyed Kassem, L.
Sood, A.
Tiktin, M.
Kulow, T.
Newman, C.
Stancil, K.A.
Cramer, B.
Iacoboni, J.
Kononets, M.V.
Sanders, C.
Tucker, L.
Werner, A.
Maxwell, A.
McPhee, G.
Patel, C.
Colosimo, L.
Krol, A.
Goland, R.
Pring, J.
Alfano, L.
Kringas, P.
Hausheer, C.
Tejada, J.
Gumpel, K.
Kirpitch, A.
Schneier, H.
Green, J.B.
AbouAssi, H.
Chatterjee, R.
Feinglos, M.N.
English Jones, J.
Khan, S.A.
Kimpel, J.B.
Zimmer, R.P.
Furst, M.
Satterwhite, B.M.
Thacker, C.R.
Evans Kreider, K.
Mariash, C.N.
Mather, K.J.
Ismail, H.M.
Lteif, A.
Mullen, M.
Hamilton, T.
Patel, N.
Riera, G.
Jackson, M.
Pirics, V.
Aguillar, D.
Howard, D.
Hurt, S.
Bergenstal, R.
Carlson, A.
Martens, T.
Johnson, M.
Hill, R.
Hyatt, J.
Jensen, C.
Madden, M.
Martin, D.
Willis, H.
Konerza, W.
Yang, S.
Kleeberger, K.
Passi, R.
Fortmann, S.
Herson, M.
Mularski, K.
Glauber, H.
Prihoda, J.
Ash, B.
Carlson, C.
Ramey, P.A.
Schield, E.
Torgrimson-Ojerio, B.
Arnold, K.
Kauffman, B.
Panos, E.
Sahnow, S.
Bays, K.
Berame, K.
Cook, J.
Ghioni, D.
Gluth, J.
Schell, K.
Criscola, J.
Friason, C.
Jones, S.
Nazarov, S.
Barzilay, J.
Rassouli, N.
Puttnam, R.
Ojoawo, B.
Nelson, R.
Curtis, M.
Hollis, B.
Sanders-Jones, C.
Stokes, K.
El-Haqq, Z.
Kolli, A.
Tran, T.
Wexler, D.
Larkin, M.
Meigs, J.
Chambers, B.
Dushkin, A.
Rocchio, G.
Yepes, M.
Steiner, B.
Dulin, H.
Cayford, M.
Chu, K.
DeManbey, A.
Hillard, M.
Martin, K.
Thangthaeng, N.
Gurry, L.
Kochis, R.
Raymond, E.
Ripley, V.
Stevens, C.
Park, J.
Aroda, V.
Ghazi, A.
Magee, M.
Ressing, Ann
Loveland, A.
Hamm, M.
Hurtado, M.
Kuhn, A.
Leger, J.
Manandhar, L.
Sanchez, O.
Young, T.
Mofor, F.
Garg, R.
Lagari-Libhaber, V.
Florez, H.J.
Valencia, W.M.
Marks, J.
Casula, S.
Oropesa-Gonzalez, L.
Hue, L.
Cuadot, A.
Nieto-Martinez, R.
Riccio Veliz, A.K.
Gutt, M.
Kendal, Y.J.
Veciana, B.
Ahmann, A.
Aby-Daniel, D.
Joarder, F.
Morimoto, V.
Sprague, C.
Yamashita, D.
Cady, N.
Rivera-Eschright, N.
Kirchhoff, P.
Morales Gomez, B.
Adducci, J.
Goncharova, A.
Hox, S.H.
Petrovitch, H.
Matwichyna, M.
Jenkins, V.
Broadwater, L.
Ishii, R.R.
Bermudez, N.O.
Hsia, D.S.
Cefalu, W.T.
Greenway, F.L.
Waguespack, C.
King, E.
Fry, G.
Dragg, A.
Gildersleeve, B.
Arceneaux, J.
Haynes, N.
Thomassie, A.
Pavlionis, M.
Bourgeois, B.
Hazlett, C.
Mudaliar, S.
Henry, R.
Boeder, S.
Pettus, J.
Diaz, E.
Garcia-Acosta, D.
Maggs, S.
DeLue, C.
Stallings, A.
Castro, E.
Hernandez, S.
Krakoff, J.
Curtis, J.M.
Killean, T.
Khalid, M.
Joshevama, E.
Tsingine, K.
Karshner, T.
Albu, J.
Pi-Sunyer, F.X.
Frances, S.
Maggio, C.
Ellis, E.
Bastawrose, J.
Gong, X.
Banerji, M.A.
August, P.
Lee, M.
Lorber, D.
Brown, N.M.
Josephson, D.H.
Thomas, L.L.
Tsovian, M.
Cherian, A.
Jacobson, M.H.
Mishko, M.M.
Kirkman, M.S.
Buse, J.B.
Dostou, J.
Machineni, S.
Young, L.
Bergamo, K.
Goley, A.
Kerr, J.
Largay, J.F.
Guarda, S.
Cuffee, J.
Culmer, D.
Fraser, R.
Almeida, H.
Coffer, S.
Debnam, E.
Kiker, L.
Morton, S.
Josey, K.
Fuller, G.
Garvey, W.T.
Cherrington, A.L.
Dyer, D.
Lawson, M.C.R.
Griffith, O.
Agne, A.
McCullars, S.
Cohen, R.M.
Craig, J.
Rogge, M.C.
Burton, K.
Kersey, K.
Wilson, C.
Lipp, S.
Vonder Meulen, M.B.
Adkins, C.
Onadeko, T.
Rasouli, N.
Baker, C.
Schroeder, E.
Razzaghi, M.
Lyon, C.
Penaloza, R.
Underkofler, C.
Lorch, R.
Douglass, S.
Steiner, S.
Sivitz, W.I.
Cline, E.
Knosp, L.K.
McConnell, J.
Lowe, T.
Herman, W.H.
Pop-Busui, R.
Tan, M.H.
Martin, C.
Waltje, A.
Katona, A.
Goodhall, L.
Eggleston, R.
Kuo, S.
Bojescu, S.
Bule, S.
Kessler, N.
LaSalle, E.
Whitley, K.
Seaquist, E.R.
Bantle, A.
Harindhanavudhi, T.
Kumar, A.
Redmon, B.
Bantle, J.
Coe, M.
Mech, M.
Taddese, A.
Lesne, L.
Smith, S.
Desouza, C.
Kuechenmeister, L.
Shivaswamy, V.
Burbach, S.
Rodriguez, M.G.
Seipel, K.
Alfred, A.
Morales, A.L.
Eggert, J.
Lord, G.
Taylor, W.
Tillson, R.
Schade, D.S.
Adolphe, A.
Burge, M.
Duran-Valdez, E.
Martinez, J.
Bancroft, A.
Kunkel, S.
Ali Jamaleddin Ahmad, F.
Hernandez McGinnis, D.
Pucchetti, B.
Scripsick, E.
Zamorano, A.
DeFronzo, R.A.
Cersosimo, E.
Abdul-Ghani, M.
Triplitt, C.
Juarez, D.
Garza, R.I.
Verastiqui, H.
Wright, K.
Puckett, C.
Raskin, P.
Rhee, C.
Abraham, S.
Jordan, L.F.
Sao, S.
Morton, L.
Smith, O.
Osornio Walker, L.
Schnurr-Breen, L.
Ayala, R.
Kreymer, R.B.
Sturgess, D.
Utzschneider, K.M.
Kahn, S.E.
Alarcon-Casas, L.
Wright, L.
Boyko, E.J.
Tsai, E.C.
Trence, D.L.
Trikudanathan, S.
Fattaleh, B.N.
Montgomery, B.K.
Atkinson, K.M.
Kozedub, A.
Concepcion, T.
Moak, C.
Prikhodko, N.
Rhothisen, S.
Elasy, T.A.
Martin, S.
Shackelford, L.
Goidel, R.
Hinkle, N.
Lovell, C.
Myers, J.
Lipps Hogan, J.
McGill, J.B.
Salam, M.
Schweiger, T.
Kissel, S.
Recklein, C.
Clifton, M.J.
Tamborlane, W.
Camp, A.
Gulanski, B.
Inzucchi, S.E.
Pham, K.
Alguard, M.
Gatcomb, P.
Lessard, K.
Perez, M.
Iannone, L.
Magenheimer, E.
Montosa, A.
Burch, H.B.
Bremer, A.A.
Fradkin, J.
Nathan, D.M.
Lachin, J.M.
Krause-Steinrauf, H.
Younes, N.
Backman, M.
Bebu, I.
Butera, N.
Buys, C.J.
Fagan Murphy, A.
Gao, Y.
Ghosh, A.
Gramzinski, M.R.
Kazemi, E.
Hall, S.D.
Legowski, E.
Suratt, C.
Tripputi, M.
Arey, A.
Bethepu, J.
Lund, C.
Mangat Dhaliwal, P.
McGee, P.
Mesimer, E.
Ngo, L.
Steffes, M.
Seegmiller, J.
Saenger, A.
Arends, V.
Gabrielson, D.
Conner, T.
Warren, S.
Day, J.
Huminik, J.
Scrymgeour, A.
Soliman, E.Z.
Pokharel, Y.
Zhang, Z.M.
Campbell, C.
Hu, J.
Keasler, L.
Hensley, S.
Li, Y.
Mihalcea, R.
Min, D.J.
Perez-Rosas, V.
Prosser, L.
Resnicow, K.
Ye, W.
Shao, H.
Zhang, P.
Luchsinger, J.
Sanchez, D.
Assuras, S.
Groessl, E.
Sakha, F.
Chong, H.
Hillery, N.
Everett, B.M.
Abdouch, I.
Bahtiyar, G.
Brantley, P.
Broyles, F.E.
Canaris, G.
Copeland, P.
Craine, J.J.
Fein, W.L.
Gliwa, A.
Hope, L.
Lee, M.S.
Meiners, R.
Meiners, V.
O’Neal, H.
Park, J.E.
Sacerdote, A.
Sledge, E.
Soni, L.
Steppel-Reznik, J.
Turchin, A.
Brooks-Worrell, B.
Hampe, C.S.
Newgard, C.B.
Palmer, J.P.
Shojaie, A.
Higgins, J.
Fischer, L.
Golden, S.
Gonzalez, J.
Naik, A.
Walker, E.
Doner Lotenberg, L.
Gallivan, J.M.
Lim, J.
Tuncer, D.M.
Source :
Diabetes Care
Publication Year :
2022
Publisher :
American Diabetes Association, 2022.

Abstract

OBJECTIVE: Differences in type 2 diabetes phenotype by age are described, but it is not known whether these differences are seen in a more uniformly defined adult population at a common early stage of care. We sought to characterize age-related clinical and metabolic characteristics of adults with type 2 diabetes on metformin monotherapy, prior to treatment intensification. RESEARCH DESIGN AND METHODS: In the Glycemia Reduction Approaches in Diabetes: A Comparative Effectiveness Study (GRADE), participants were enrolled who had type 2 diabetes duration

Subjects

Subjects :
Clinical Care/Education/Nutrition/Psychosocial Research

Details

Language :
English
Database :
OpenAIRE
Journal :
Diabetes Care
Accession number :
edsair.pmc...........57a1778a7d9a4a6235fdb91507c3e915

Tools

Authors Abstract Subjects Details