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Analysis of mRNA and Protein Levels of
- Source :
- International journal of molecular sciences. 23(3)
- Publication Year :
- 2021
-
Abstract
- Schizophrenia (SCZ) is a mental illness characterized by aberrant synaptic plasticity and connectivity. A large bulk of evidence suggests genetic and functional links between postsynaptic abnormalities and SCZ. Here, we performed quantitative PCR and Western blotting analysis in the dorsolateral prefrontal cortex (DLPFC) and hippocampus of SCZ patients to investigate the mRNA and protein expression of three key spine shapers: the actin-binding protein cyclase-associated protein 2 (
- Subjects :
- Adult
Aged, 80 and over
Male
Membrane Proteins
Parkinson Disease
Middle Aged
Hippocampus
Discs Large Homolog 1 Protein
ADAM10 Protein
Dorsolateral Prefrontal Cortex
Gene Expression Regulation
Alzheimer Disease
Case-Control Studies
Schizophrenia
Humans
Female
Autopsy
Amyloid Precursor Protein Secretases
Adaptor Proteins, Signal Transducing
Aged
Subjects
Details
- ISSN :
- 14220067
- Volume :
- 23
- Issue :
- 3
- Database :
- OpenAIRE
- Journal :
- International journal of molecular sciences
- Accession number :
- edsair.pmid..........01b2a1e890a0a63e510b03cf4c74f4d0