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[Association between life style, diet intake and high risk-human papillomavirus persistent infection among rural women in Xinmi City, Henan Province]

Authors :
Xiaoqin, Lei
Wen, Chen
Lulu, Yu
Zeni, Wu
Yu, Qin
Gao Guoqi
Fengxian, Zheng
Caihong, Li
Xuemei, Lian
Source :
Wei sheng yan jiu = Journal of hygiene research. 45(1)
Publication Year :
2016

Abstract

To explore the association between life style, diet intake and high risk human papillomavirus (HR-HPV) persistent infection among Chinese rural women living in Xinmi City, Henan Province.In 2010, a 3-year prospective study in which 2500 women were enrolled and screened by different HR-HPV DNA tests was conducted, part of women among them was followed and tested for HR-HPV DNA in 2012 and 2014. Furthermore, socio demographic factors, gynecological information and diet intake in the past 12 months were collected by self-designed questionnaire in 2014. A total of 721 women with complete test results were eligible for the final analysis. Study participants were divided into 3 groups (persistent infection group, transient infection group, and negative group) by HR-HPV status, and the association between life style, diet intake and HR-HPV persistence was evaluated using ordinal logistic regression model.The average age of 721 women included in the analysis was 50 years old. 141 women had HR-HPV persistent infection, 180 women had HR-HPV transient infection, and 400 women were negative for HR-HPV in 3 years. Age (Χ2 = 58.449, P0.001, P(trend)0.001), smoking (Χ2 = 6.981, P = 0.021), contraception method (Χ2 = 8.448, P = 0.015) , menopause (Χ2 = 35.712, P0.001), number of live births (Χ2 = 16.340, P0.001, P(trend)0.001), and the intake frequency of cereals (Χ2 = 17.937, P = 0.001) or others (Χ2 = 12.107, P = 0.017) varied significantly between women grouped by different HR-HPV status. Compared to women who were older than 59 years, women in the younger groups had a much lower risk of HR-HPV persistence (adjusted OR1 = 0.39, 95% CI 0.26 - 0.59, OR2 = 0.40, 95% CI 0.23 - 0.69, and OR3 = 0.28, 95% CI 0.12 - 0.68).Age is the main risk factor of HR-HPV persistent infection. Lifestyle, diet intake do not associate with HR-HPV persistence after adjustment by age.

Details

ISSN :
10008020
Volume :
45
Issue :
1
Database :
OpenAIRE
Journal :
Wei sheng yan jiu = Journal of hygiene research
Accession number :
edsair.pmid..........0c748b84d47da1c3c82db4256ab41718