The development of the dentate nucleus in man

The development of the dentate nucleus was studied on 12 brains of the human fetuses of different crown-rump length (CRL) and one newborn. The first appearance of the dentate nucleus was noticed in the fetus 12.5 weeks old. The dorsomedial lamina begins to grow in the 13th week and to fold in the 20th week. The ventrolateral lamina begins to grow in the 20th week and to fold in the 23.5th week. During the development of the dentate nucleus, 2 important periods can be determined. The first period corresponds to the first appearance of the dentate nucleus (12.5 weeks) and the second period corresponds to intensive growth of the dorsomedial and ventrolateral lamina (20-24.5 weeks).