A Notch/STAT3-driven Blimp-1/c-Maf-dependent molecular switch induces IL-10 expression in human CD4

Authors :: Jonas, Ahlers
Andrej, Mantei
Laura, Lozza
Manuela, Stäber
Frederik, Heinrich
Petra, Bacher
Thordis, Hohnstein
Lutz, Menzel
Simge G, Yüz
Daniel, Alvarez-Simon
Anne Rieke, Bickenbach
Carl, Weidinger
Nadine, Mockel-Tenbrinck
Anja A, Kühl
Britta, Siegmund
Jochen, Maul
Christian, Neumann
Alexander, Scheffold
Source :: Mucosal immunology. 15(3)
Publication Year :: 2021
Abstract: Immunosuppressive Interleukin (IL)-10 production by pro-inflammatory CD4

Subjects :: Mice, Knockout
STAT3 Transcription Factor
Mice
Crohn Disease
Proto-Oncogene Proteins c-maf
Animals
Humans
Th1 Cells
Inflammatory Bowel Diseases
Interleukin-10

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