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Driven to autoimmunity: the nod mouse

Authors :
Alena M, Gallegos
Michael J, Bevan
Source :
Cell. 117(2)
Publication Year :
2004

Abstract

In the lymphoid system, T cells respond to space or under-crowding by dividing to maintain their numbers. In this issue of Cell, evidence is provided that this homeostatic proliferation, coupled with excess production of a cytokine, IL-21, is a key factor in susceptibility to autoimmune diabetes.

Details

ISSN :
00928674
Volume :
117
Issue :
2
Database :
OpenAIRE
Journal :
Cell
Accession number :
edsair.pmid..........28a62084719cd854b66c7b6b172200d1