IL-22 Preserves Gut Epithelial Integrity and Promotes Disease Remission during Chronic

Authors :: Bernard C, Lo
Samuel B, Shin
Diana, Canals Hernaez
Ido, Refaeli
Hong B, Yu
Verena, Goebeler
Alissa, Cait
William W, Mohn
Bruce A, Vallance
Kelly M, McNagny
Source :: Journal of immunology (Baltimore, Md. : 1950). 202(3)
Publication Year :: 2018
Abstract: The cytokine IL-22 is rapidly induced at barrier surfaces where it regulates host-protective antimicrobial immunity and tissue repair but can also enhance disease severity in some chronic inflammatory settings. Using the chronic

Subjects :: Inflammation
Salmonella typhimurium
Salmonella Infections, Animal
Interleukins
Remission Induction
Antibodies, Bacterial
Antibodies, Neutralizing
Gastroenteritis
Gastrointestinal Microbiome
Mice, Inbred C57BL
Mice
Crohn Disease
Animals
Bacteroides
Cytokines
Intestinal Mucosa
Cecum

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