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Patient stratification for determining optimal second-line and third-line therapy for type 2 diabetes: the TriMaster study

Authors :
Beverley M, Shields
John M, Dennis
Catherine D, Angwin
Fiona, Warren
William E, Henley
Andrew J, Farmer
Naveed, Sattar
Rury R, Holman
Angus G, Jones
Ewan R, Pearson
Andrew T, Hattersley
Source :
Nature medicine.
Publication Year :
2022

Abstract

Precision medicine aims to treat an individual based on their clinical characteristics. A differential drug response, critical to using these features for therapy selection, has never been examined directly in type 2 diabetes. In this study, we tested two hypotheses: (1) individuals with body mass index (BMI) 30 kg/m

Details

ISSN :
1546170X
Database :
OpenAIRE
Journal :
Nature medicine
Accession number :
edsair.pmid..........2ff9f3061495f5008a7d91e32307a334