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Pancreatic Disorders in Patients with Inflammatory Bowel Disease
- Source :
- Digestive diseases and sciences. 67(2)
- Publication Year :
- 2020
-
Abstract
- Inflammatory bowel disease (IBD) can involve multiple organ systems, and pancreatic manifestations of IBD are not uncommon. The incidence of several pancreatic diseases is more frequent in patients with Crohn's disease and ulcerative colitis than in the general population. Pancreatic manifestations in IBD include a heterogeneous group of disorders and abnormalities ranging from mild, self-limited disorders to severe diseases. Asymptomatic elevation of amylase and/or lipase is common. The risk of acute pancreatitis in patients with IBD is increased due to the higher incidence of cholelithiasis and drug-induced pancreatitis in this population. Patients with IBD commonly have altered pancreatic histology and chronic pancreatic exocrine dysfunction. Diagnosing acute pancreatitis in patients with IBD is challenging. In this review, we discuss the manifestations and possible causes of pancreatic abnormalities in patients with IBD.
- Subjects :
- Pancreatitis, Alcoholic
Autoimmune Pancreatitis
Anti-Inflammatory Agents, Non-Steroidal
Cholangitis, Sclerosing
Inflammatory Bowel Diseases
Anti-Bacterial Agents
Pancreatic Neoplasms
Crohn Disease
Pancreatitis
Cholelithiasis
Pancreatitis, Chronic
Azathioprine
Humans
Colitis, Ulcerative
Marijuana Use
Tumor Necrosis Factor Inhibitors
Mesalamine
Glucocorticoids
Immunosuppressive Agents
Subjects
Details
- ISSN :
- 15732568
- Volume :
- 67
- Issue :
- 2
- Database :
- OpenAIRE
- Journal :
- Digestive diseases and sciences
- Accession number :
- edsair.pmid..........3c9e79be09096be6318091845901825e