[Research advances of autophagy in sensorineural hearing loss]

Authors :: M, Chu
J R, Shi
Y, Dong
Source :: Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery. 55(1)
Publication Year :: 2020
Abstract: 自噬是细胞在生理或病理因子作用下，通过溶酶体途径对功能受损的蛋白质和细胞器进行识别降解的一种现象。近年来研究发现自噬在感音神经性聋中起着重要作用，可通过参与毛细胞的氧化应激、能量代谢或与凋亡相互作用等途径影响感音神经性聋的发生发展。本文就不同损伤因素如遗传基因缺陷、耳毒性药物、衰老和噪声暴露等所致感音神经性聋的自噬机制进行探讨，旨在为感音神经性聋的预防及治疗提供新的思路。.

Subjects :: Biomedical Research
Hearing Loss, Sensorineural
Autophagy
Humans

ISSN :: 16730860
Volume :: 55
Issue :: 1
Database :: OpenAIRE
Journal :: Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery
Accession number :: edsair.pmid..........3f70225992fbaa4a66be8499c50d23fe

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