Sexual dimorphism in prostacyclin-mimetic responses within rat mesenteric arteries: A novel role for K

Prostacyclin mimetics express potent vasoactive effects via prostanoid receptors that are not unequivocally defined, as to date no study has considered sex as a factor. The aim of this study was to determine the contribution of IP and EPWithin second-order mesenteric arteries from male and female Wistar rats, we determined (1) relative mRNA transcripts for EPIloprost evoked a biphasic response in male mesenteric arteries, at concentrations ≤100 nmol·LStark sexual dimorphisms in iloprost-mediated vasoactive responses are present within mesenteric arteries. K