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Studies on production of biologically active substances which inhibit cell migration in supernatants and extracts hypersensitive lymphoid cells incubated with specific antigen in vitro
- Publication Year :
- 1968
-
Abstract
- When lymphoid cells from hypersensitive rabbits are incubated with antigen, biologically active substances are formed and released which are capable of inhibiting the migration of normal non-sensitized mesenchymal cells. In the present paper some basic parameters of their production were determined. These substances were regularly obtained after 6 and 18 hours incubation, but not after 2 hours. Under more favourable cultivation conditions (lower density of lymphocyte suspension) an increased activity in the cell extracts as compared with the supernatants was observed.
Details
- Language :
- English
- Database :
- OpenAIRE
- Accession number :
- edsair.pmid..........4958612044e559e29ce5c76a809c8038