A Subset of Mycobacteria-Specific CD4

Authors :: Jinyun, Yuan
Janice, Tenant
Thomas, Pacatte
Christopher, Eickhoff
Azra, Blazevic
Daniel F, Hoft
Soumya, Chatterjee
Source :: Journal of immunology (Baltimore, Md. : 1950). 203(4)
Publication Year :: 2019
Abstract: Failure of the most recent tuberculosis (TB) vaccine trial to boost bacillus Calmette-Guérin-mediated anti-TB immunity despite the induction of Th1-specific central memory cell and effector memory cell responses highlights the importance of identifying optimal T cell targets for protective vaccines. In this study, we describe a novel