Secreted phospholipase A

Authors :: Kai, Kudo
Yoshimi, Miki
Joaquim, Carreras
Shunya, Nakayama
Yasushi, Nakamoto
Masatoshi, Ito
Etsuko, Nagashima
Kei, Yamamoto
Hiroshi, Higuchi
Shin-Ya, Morita
Asuka, Inoue
Junken, Aoki
Kiyoshi, Ando
Naoya, Nakamura
Makoto, Murakami
Ai, Kotani
Source :: Cell metabolism. 34(4)
Publication Year :: 2021
Abstract: Extracellular vesicles (EVs) including exosomes act as intercellular communicators by transferring protein and microRNA cargoes, yet the role of EV lipids remains unclear. Here, we show that the pro-tumorigenic action of lymphoma-derived EVs is augmented via secreted phospholipase A