[Low grade adenosquamous carcinoma arising from sclerosing adenosis of the breast: report of a case]

Authors :: L M, Fu
X J, Sun
H, Lyu
R H, Shui
X L, Xu
W T, Yang
Source :: Zhonghua bing li xue za zhi = Chinese journal of pathology. 48(5)
Publication Year :: 2019
Abstract: 患者女，53岁，因发现"右乳肿块1个月余"就诊。肿物直径约1.3 cm，灰白色，质韧。镜下病变界尚清，2/3的区域为硬化性腺病，另1/3的区域硬化性间质中杂乱分布着小腺管以及鳞状分化细胞巢，鳞化细胞巢多呈实性条索状，部分形成大小不等的角化囊肿；病变细胞形态温和，核分裂象罕见，并见淋巴细胞聚集灶，局灶浸润周围组织。免疫组织化学显示该区域内大部分细胞巢周围缺乏p63、calponin及CD10染色，部分鳞状分化巢CK5/6和p63阳性，诊断为乳腺硬化性腺病基础上的低级别腺鳞癌。.

Subjects :: Diagnosis, Differential
Carcinoma, Adenosquamous
Sclerosis
Humans
Breast Neoplasms
Female
Breast
Fibrocystic Breast Disease

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