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Effect of homologous tumor DNA on the evolution of SV40-induced hamster sarcoma
- Source :
- Virologie. 36(1)
- Publication Year :
- 1985
-
Abstract
- DNA extracted from SV40-induced hamster sarcoma (SV40--HS DNA) increased the survival length of animals carrying the homologous tumor and--in some cases--inhibited the development of the tumor. The efficacy of the preparation was directly proportional to the number of administrations; it did not necessarily depend on the amount of SV40--HS DNA per dose. SV40 DNA had no favourable effect on the evolution of the SV40-induced tumor, which suggests that viral DNA does not represent the active component of the SV40--HS DNA preparations. Some possible mechanisms of the effect of homologous tumor preparations are discussed.
Details
- ISSN :
- 0253181X
- Volume :
- 36
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- Virologie
- Accession number :
- edsair.pmid..........6652942652afba838ca434cc45f7ab3a