Azoospermia in dogs induced by injection of sclerosing agents into the caudae of the epididymides

Injections of sclerosing agents into the caudae of the epididymides of adult and prepubertal dogs induced a long-lasting and probably irreversible azoospermia. The technique is easy to do and inexpensive, does not seem to cause undesirable side effects, and appears suitable for large-scale sterilization programs in male dogs.Azoospermia in dogs induced by injection of sclerosing agents into the caudae of the epididymides was investigated. Treatment with formalin induced temporary azoospermia or oligospermia in all treated dogs; testicular diameter increased significantly (p less than .05) on Days 5 and 7 after treatment. The 2 dogs teated with 1.5% chlorhexidine gluconate in 50% DMSO became azoospermic for the duration of the study. Treatment with a 3.3% solution of formalin in .05 M phosphate-buffered saline solution induced temporary azoospermia or oligospermia. The technqiue described is effective, easy to apply, inexpensive, does not seem to cause undesirable side effects, and appears suitable for large-scale sterilization in male dogs.