Back to Search Start Over

Development of a High-Throughput Screening Assay to Identify Inhibitors of the Major M17-Leucyl Aminopeptidase from

Authors :
Maikel, Izquierdo
De, Lin
Sandra, O'Neill
Martin, Zoltner
Lauren, Webster
Anthony, Hope
David W, Gray
Mark C, Field
Jorge, González-Bacerio
Source :
SLAS discovery : advancing life sciences RD. 25(9)
Publication Year :
2020

Abstract

Leucyl aminopeptidases (LAPs) are involved in multiple cellular functions, which, in the case of infectious diseases, includes participation in the pathogen-host cell interface and pathogenesis. Thus, LAPs are considered good candidate drug targets, and the major M17-LAP from

Details

ISSN :
24725560
Volume :
25
Issue :
9
Database :
OpenAIRE
Journal :
SLAS discovery : advancing life sciences RD
Accession number :
edsair.pmid..........6b0e0d3938a36a8da5693b9799b02641