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[Radioembolization with (90)Y-labeled microspheres: post-therapeutic therapy validation with Bremsstrahlung-SPECT]

Authors :
Oliver S, Grober
Madeleine, Nultsch
Kathleen, Laatz
Gerd, Ulrich
Ricarda, Seidensticker
Annette, Pethe
Oliver, Dudeck
Maciej, Pech
Bernd O, Knoop
Jens, Ricke
Holger, Amthauer
Lilli, Geworski
Source :
Zeitschrift fur medizinische Physik. 21(4)
Publication Year :
2011

Abstract

During the last years angiographic Selective Internal Radiotherapy (SIRT) with (90)Y-labelled microspheres has become a common technique for the local-ablative treatment of cancer patients. SIRT is a palliative therapy concept for the treatment of liver malignancies. As a result of (90)Y-decay as β(-)-emitter without a concomitant gamma radiation, Bremsstrahlung imaging is needed to validate the distribution achieved by radioembolisation. This article demonstrates the method of imaging through phantom measurement and shows the advantages of post-therapeutic tomography by means of a patient study. Approaches for further optimization of Bremsstrahlung imaging are discussed.

Details

Language :
German
ISSN :
18764436
Volume :
21
Issue :
4
Database :
OpenAIRE
Journal :
Zeitschrift fur medizinische Physik
Accession number :
edsair.pmid..........6b84eb1e476a977e98270c0542f961ec